Research Topic · Peer-Reviewed

Pyruvate

Dehydrogenase Pyruvate Dehydrogenase (PDH) is an enzyme that plays an essential role in the metabolism of glucose. It is the primary enzyme responsible for the conversion of pyruvate, a product of glycolysis, into Acetyl-CoA, which enters the Krebs cycle to produce energy in the form of ATP. PDH is also involved in…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 53× across the literature 🗓 Reviewed June 2026

Overview

Dehydrogenase Pyruvate Dehydrogenase (PDH) is an enzyme that plays an essential role in the metabolism of glucose. It is the primary enzyme responsible for the conversion of pyruvate, a product of glycolysis, into Acetyl-CoA, which enters the Krebs cycle to produce energy in the form of ATP. PDH is also involved in numerous other biochemical pathways related to energy production and storage, protein and lipid metabolism, and various other metabolic pathways. As such, it plays a pivotal role in the body’s energy production and storage processes. Defects in PDH can lead to serious metabolic disorders including lactic acidosis, neurodegenerative diseases, and anaemia. Therefore, PDH is an important enzyme for understanding the various biochemical processes that regulate energy metabolism and storage.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 53 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Pyruvate, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Advanced Cytology.

Journal editorial board
Krzysztof Marycz · Poland MARIA VIOLETTA BRUNDO · Italy

This page summarises published research for orientation; it is not medical or professional advice.