Systems Biology

Overview

Systems biology is the study of biological systems as integrated networks rather than collections of isolated parts. It combines experimental data with computational, mathematical and bioinformatic methods to understand how genes, proteins, metabolites and other components interact to produce the behaviour of cells, tissues and organisms. By modelling these networks, systems biology seeks to explain emergent properties, predict how systems respond to perturbation, and inform applications such as diagnostics, personalised medicine and drug discovery. Reflecting the cross-disciplinary scope of this journal and its companion titles, related research has applied integrative and computational approaches to biological problems. Studies include proteomic and genomic techniques in medical research with applications in cancer, diagnostics and personalised medicine, bioinformatic resources for diabetic nephropathy, the bioinformatics of metabolomics in type 2 diabetes, and a network-pharmacology strategy for predicting therapeutic targets. This page gathers peer-reviewed, open-access research relevant to systems biology and the use of high-throughput data and computational modelling to understand complex biological networks.

Research published in this journal

6 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 6 articles above have been cited 9 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

• A decision support system based on artificial intelligence and systems biology for the simulation of pancreatic cancer patient status
  2023 · CPT Pharmacometrics & Systems Pharmacology
• A decision support system based on artificial intelligence and systems biology for the simulation of pancreatic cancer patient status
  2023 · CPT: Pharmacometrics & Systems Pharmacology
• Diabetic Nephropathy Assessment: Microtubule-Associated Protein 1 Light-Chain 3B a New Promising Biomarker
  2019 · Indian Journal of Clinical Biochemistry
• Functional, Structural And Contextual Analysis Of A Variant Of Uncertain Clinical Significance In BRCA1: C.5434c->G (p.pro1812ala)
  2017 · Journal of Cancer Genetics and Biomarkers
• Increased Plasma Levels of Xanthurenic and Kynurenic Acids in Type 2 Diabetes
  2015 · Molecular Neurobiology
• Genetics of Diabetic Nephropathy: a Long Road of Discovery
  2015 · Current Diabetes Reports
• Increased Plasma Levels of Xanthurenic and Kynurenic Acids in Type 2 Diabetes
  G. Oxenkrug · 2015 · Molecular Neurobiology
• Genetic and epigenetic risk factors for diabetic kidney disease.
  A. McKnight et al. · 2014 · Advances in Chronic Kidney Disease

A sample of recent works citing this journal's research on Systems Biology, linking to each citing work.

This page summarises published research for orientation; it is not medical or professional advice.

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