Gerhard Meissner
Pi, University of North Carolina, Chapel Hill, NC · United States
Editorial leadership for Journal of Skeletal Muscle ISSN 2832-4048
Research interests
- Excitation-Contraction Coupling Ryanodine Receptor Sarcoplasmic Reticulum
Biography
Gerhard Meissner is affiliated with the University of North Carolina, Chapel Hill, NC, United States. His research has focused on the structure and function of ryanodine receptor ion channels in skeletal and cardiac muscle, investigating channel gating mechanisms, regulatory domains, and modulation by calmodulin, nitric oxide, and redox-sensitive cysteines. His work has elucidated the roles of pore lining residues, cytosolic vestibule charges, and lumenal loops in determining ion channel conductance and activity, as well as the coupling of oxygen sensing and nitric oxide signaling functions in skeletal muscle calcium release channels. His most-cited publication, "The structural basis of ryanodine receptor ion channel function" (2017), has been cited 208 times and represents a significant contribution to understanding these critical calcium signaling complexes.
Selected publications
- The structural basis of ryanodine receptor ion channel function 2017 cited 208×
- Ca2+-mediated activation of the skeletal-muscle ryanodine receptor ion channel 2018 cited 31×
- Structural and functional interactions between the Ca2+-, ATP-, and caffeine-binding sites of skeletal muscle ryanodine receptor (RyR1) 2021 cited 25×
- Single-channel properties of skeletal muscle ryanodine receptor pore Δ4923FF4924 in two brothers with a lethal form of fetal akinesia 2020 cited 7×
Ranked by citation impact (Crossref) where available, newest otherwise · verified via ORCID.
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This journal is guided by Gerhard Meissner (Pi, University of North Carolina, Chapel Hill, NC) and a peer-review board of practising researchers. Open access, author-retained copyright (CC BY), and a clear editorial process.