Author Instructions
Instructions for Authors: Immunology and Geriatrics
Prepare reproducible manuscripts with strong clinical relevance for aging populations.
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Use standard sections: Title, Abstract, Keywords, Introduction, Methods, Results, Discussion, Conclusion, References, Funding, Conflicts, and Data Availability.
Abstracts should state study design, main findings, and implications for immune health in older adults. Keywords should include disease context, immune pathway terms, and geriatric descriptors.
Define abbreviations at first use and maintain consistency across text, figures, and supplementary files.
Describe cohort characteristics, inclusion and exclusion criteria, lab protocols, assay parameters, and analytical methods in sufficient detail for replication.
For omics or high-dimensional analyses, report software versions, model settings, quality control thresholds, and validation strategy.
Clinical studies should include ethics approval identifiers, consent procedures, and privacy safeguards for age-related and potentially sensitive data.
P
Population Detail
Report baseline characteristics and subgroup definitions clearly.
M
Model Transparency
Describe assumptions, fit diagnostics, and validation method.
S
Sensitivity Analysis
Assess robustness where confounding risk is high.
U
Uncertainty
Report intervals and limitation context, not only point estimates.
Figures must include clear legends, units, and cohort context. Tables should present complete variable definitions and avoid ambiguous abbreviations.
Supplementary data files should be named systematically and mapped explicitly from the main text. Include protocol details and code references when required for interpretation.
Ensure cross-references between manuscript, appendices, and repository identifiers are consistent.
Include ethics approval statements, informed consent details, funding declarations, conflicts of interest, and data sharing conditions.
If data cannot be open, provide controlled-access rationale and request pathway. Similarity checks and integrity assessments are part of standard editorial processing.
Authorship changes after submission require documented consent from all authors.
1
Prepare Files
Finalize manuscript, declarations, and supplementary materials.
2
Choose Route
Submit through ManuscriptZone or the simple submission form.
3
Peer Review
Editors assign qualified reviewers and manage revision cycles.
4
Publication
Accepted papers move to production, licensing, and indexing.
Address each reviewer point directly and indicate exact manuscript changes. Provide rationale when recommendations are not implemented.
At proof stage, verify author details, figures, references, and metadata terms carefully to avoid post-publication corrections.
For complex submissions, contact [email protected] early with manuscript ID and question type for faster support routing.
Author Control Board
This board is designed for teams that want cleaner technical checks, fewer revision loops, and faster progression from editorial triage to external review. Instead of one long checklist, the workflow is segmented into control gates that map to the most common rejection or delay triggers in immunology and geriatrics submissions.
6Control Gates
3Risk Layers
4Execution Stages
1Owner Model
Scope Clarity
Method Fidelity
Statistical Control
Ethics Governance
Evidence Mapping
Production Readiness
01
Scope and Framing Lock
Align title, abstract, key message, and conclusion to one coherent contribution statement before upload. For immunology and geriatrics, framing must connect mechanism or intervention with practical implications for older populations. If those layers are disconnected, triage quality scores drop quickly and reviewers may interpret the work as conceptually unfinished.
02
Design and Protocol Precision
Declare design class with precision and keep it stable across all sections: observational, interventional, retrospective, prospective, registry, or mixed model. Include setting, recruitment window, eligibility logic, and protocol adaptation notes. Precise design language is one of the fastest ways to increase reviewer trust before deeper statistical assessment begins.
03
Statistical Governance
Lock endpoint names across manuscript text, tables, figures, and supplements. State confounder strategy, missing-data handling, subgroup boundaries, and sensitivity checks in one reproducible chain. When endpoint labels drift or model assumptions are scattered, reviewers often request major clarification rounds that can be prevented by one coordinated preflight review.
04
Ethics and Data Rights
Synchronize ethics approval identifiers, consent pathway, funding statements, conflict declarations, and data availability language across every submission artifact. If data access is controlled, define the request authority and access conditions explicitly. Administrative holds commonly start here, so governance consistency is a direct speed lever for first-round processing.
05
Evidence and Asset Mapping
Map each major claim to one concrete evidence object: figure panel, table line, or supplementary item. Verify that legends, units, abbreviations, and file names remain consistent from draft to final upload. Clear mapping improves reviewer navigation and reduces uncertainty about whether results are fully supported by documented evidence.
06
Revision and Production Control
Prepare a line-referenced rebuttal format before reviewer comments arrive so revision cycles stay disciplined. In parallel, pre-confirm affiliation format, repository links, and figure permissions for production handoff. Manuscripts with pre-defined response and production controls are less likely to stall after acceptance and usually publish faster.
Failure Pattern: Fragmented Ownership
Most avoidable delays come from distributed accountability where methods, declarations, and supplements are owned by different coauthors without final harmonization. Assign one readiness owner with authority to freeze terminology, reconcile declarations, and approve final file packaging. Central ownership improves consistency and decreases correction risk at every stage.
Performance Pattern: Decision-Ready Files
High-performing submissions are not simply complete. They are decision-ready, meaning reviewers can validate design logic, evidence path, and governance status without extra requests. Decision-ready files receive more focused scientific feedback, experience fewer technical interruptions, and move to publication with better timeline predictability.
Quality Pattern: Controlled Narrative Density
Strong manuscripts use precise, information-dense language without overwhelming reviewers with unstructured text blocks. Keep scientific depth high, but segment interpretation into clearly labeled logic units so readers can trace claim, evidence, and limitation in sequence. Controlled narrative density improves comprehension speed, strengthens editorial confidence, and reduces misinterpretation during peer review rounds.
07
Reference Integrity and Citation Control
Before submission, run a complete citation audit and verify every source against manuscript claims. Mechanistic statements should be anchored in primary evidence wherever possible, while clinical recommendations should rely on current systematic or consensus-level sources. Citation integrity is not cosmetic: weak reference structure directly lowers reviewer confidence in interpretation quality and novelty positioning.
08
Translational Utility Verification
Validate that the discussion answers three practical questions: who benefits, how findings can be applied, and what implementation boundaries still exist. Manuscripts that clearly connect results to actionable care, policy, or research planning are easier to route editorially and often perform better with multidisciplinary reviewer panels assessing real-world relevance.
09
Multicenter Coordination Discipline
For multicenter teams, set one final synchronization checkpoint before upload to reconcile terminology, sample-size reporting, ethics language, and supplement version control. In distributed collaborations, this single checkpoint is frequently the difference between smooth technical screening and repeated correction cycles. Operational discipline at this stage saves substantial review and production time later.
Final preflight recommendation: run the full board with one reviewer who was not involved in drafting the manuscript. Fresh internal review often surfaces missing logic links, unclear endpoints, and declaration gaps that core authors no longer notice. That independent check is a low-cost way to improve first-round decision quality.
Execution principle: quality gains come from sequence control, not isolated edits. Run the gates in order, document completion status, and submit only after all controls are locked.
1Audit
Run one unified quality sweep across manuscript, visuals, and declarations.
2Submit
Use ManuscriptZone or the simple route with the same control standards.
3Revise
Respond with line-referenced evidence and explicit implementation notes.
4Publish
Confirm proof metadata and rights details before final release.
Final execution rule: keep one corresponding author accountable from submission through proof approval, with clear response ownership for technical, ethical, and production queries. If your team needs pre-submission alignment support, contact [email protected] with manuscript title, article type, and question category before upload. Early coordination usually prevents the delays that cost the most time later in peer review and publication workflows.
Submit Your Manuscript to JIG
Follow these instructions to reduce revision cycles and improve publication readiness.
For support: [email protected]