Aims & Scope
International Journal of Biochemistry Advances (IJBA) publishes molecular-level research on chemical structures, reaction mechanisms, and biochemical pathways that advance our understanding of biological systems through chemistry. We emphasize mechanistic insights, structural characterization, and chemical synthesis. Studies may involve cellular, organismal, environmental, or clinical samples, but manuscripts in which clinical applications or patient outcomes are the primary focus fall outside our scope.
Research Domains
Molecular Biochemistry
- Protein structure-function relationships and folding dynamics
- Nucleic acid chemistry and molecular interactions
- Lipid biochemistry and membrane structure
- Carbohydrate chemistry and glycosylation mechanisms
- Enzyme kinetics and catalytic mechanisms
- Cofactor chemistry and metal ion coordination
Metabolic Pathways & Regulation
- Glycolysis, TCA cycle, and oxidative phosphorylation mechanisms
- Lipid metabolism and fatty acid oxidation chemistry
- Amino acid metabolism and nitrogen cycle biochemistry
- Redox biochemistry and electron transfer chains
- Allosteric regulation and feedback inhibition mechanisms
- Metabolite signaling and chemical messengers
Chemical Synthesis & Drug Development
- Organic synthesis of bioactive molecules
- Drug metabolism and biotransformation pathways
- Structure-activity relationships (SAR) of pharmaceuticals
- Chemical modification of biomolecules
- Synthesis of enzyme inhibitors and activators
- Prodrug design and chemical stability studies
Analytical & Physical Biochemistry
- Spectroscopic methods (NMR, UV-Vis, fluorescence, IR)
- Mass spectrometry and proteomics
- Chromatographic separation techniques
- Thermodynamic analysis of biomolecular interactions
- Structural biology methods (X-ray, cryo-EM, SAXS)
- Biophysical characterization of macromolecules
Secondary Focus Areas
Biotechnology Applications
- Enzyme engineering and directed evolution
- Biocatalysis and green chemistry
- Recombinant protein production
- Biosensor development and chemical detection
- Nanomaterial-biomolecule conjugates
Computational Chemistry
- Molecular dynamics simulations
- Quantum chemical calculations
- Docking studies and binding affinity prediction
- QSAR modeling
- Machine learning for property prediction
Plant & Agricultural Biochemistry
- Phytochemical isolation and characterization
- Plant secondary metabolite biosynthesis
- Photosynthesis mechanisms
- Plant hormone chemistry
- Agricultural chemical development
Toxicology & Chemical Safety
- Xenobiotic metabolism pathways
- Reactive oxygen species (ROS) chemistry
- Genotoxicity mechanisms at molecular level
- Antioxidant chemistry and radical scavenging
- Chemical mutagenesis mechanisms
Emerging Research Areas
Chemical Biology
- Chemical probes for biological systems
- Activity-based protein profiling
- Bioorthogonal chemistry
- Chemical genetics approaches
Systems Biochemistry
- Metabolomics and lipidomics
- Network analysis of metabolic pathways
- Flux balance analysis
- Multi-omics integration (chemical focus)
Note: Emerging area submissions undergo additional editorial review to ensure alignment with the journal's molecular and chemical focus. Interdisciplinary work must demonstrate clear biochemical mechanisms.
Article Types & Priorities
Fast-Track
Standard Review
Manuscript Requirements: Original research must include detailed experimental methods, spectroscopic characterization, statistical analysis, and raw data availability. Computational studies must provide validation against experimental data. Reviews must be comprehensive and cite primary literature extensively.
Editorial Standards
Reporting Guidelines
All submissions must follow discipline-appropriate reporting standards to ensure reproducibility and transparency.
Data Transparency
Raw data, spectroscopic files, crystallographic coordinates, and computational scripts must be deposited in public repositories (PDB, BMRB, Zenodo, GitHub).
Ethics & Compliance
Animal studies require institutional ethics approval. Human samples require informed consent. Chemical safety protocols must be documented. Conflicts of interest must be declared.
Preprint Policy
We accept submissions previously posted on preprint servers (ChemRxiv, bioRxiv, arXiv). Preprint DOI must be disclosed at submission.
Publication Metrics
Average Time to
First Decision
Acceptance Rate
(2023)
Publication After
Acceptance
Access Model
(CC BY 4.0)
Ready to Submit?
If your research focuses on molecular mechanisms, chemical structures, or biochemical pathways—and aligns with our scope—we invite your submission.
Submit Your ManuscriptQuestions about scope fit? Contact our editorial team at [email protected]
